Background: To build a reference curve for the area of Wharton�s jelly (WJ) in low-risk pregnancies from 13 to 40\r\nweeks and to assess its relationship with estimated fetal weight (EFW).\r\nMethods: 2,189 low-risk pregnancies had the area of WJ estimated by ultrasound and the 10th, 50th and 90th\r\npercentiles calculated using a third-degree polynomial regression procedure. EFW by ultrasound was correlated\r\nwith the measurement of the area of WJ.\r\nResults: The area of WJ increased according to gestational age (R2 = 0.64), stabilizing from the 32nd week onwards.\r\nThere was a significant linear correlation between area of WJ and EFW up to 26 weeks (R = 0.782) and after that 5t\r\nremained practically constant (R = 0.047).\r\nConclusion: The area of WJ increases according to gestational age, with a trend to stabilize at around 32 weeks of\r\ngestation. It is also linearly correlated with EFW only up to 26 weeks of gestation.
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